GLP-1 Weight Loss Special - New Clients Start Same Day for only $99
GLP-1 Weight Loss Special - New Clients Start Same Day for only $99
Tesofenisine is a prescription option designed to reduce appetite and improve metabolic control—helping you eat less without “white-knuckle” cravings, and supporting steady energy as you lose weight. It modulates key brain neurotransmitters involved in appetite and satiety (serotonin, dopamine, norepinephrine).
Tesofenisine is a triple monoamine reuptake inhibitor (MRI)—it helps keep more of three messengers active in the brain: norepinephrine, dopamine, and serotonin. Those messengers play a major role in hunger, reward, and fullness signals.
Tesofensine increases serotonin activity in the brain, which helps amplify feelings of fullness after meals. This means you can feel satisfied with smaller portions, making it easier to stay on track without constant hunger. Over time, this appetite regulation reduces daily caloric intake significantly.
By elevating dopamine, Tesofensine improves the brain’s reward regulation pathways, which can help curb impulsive eating. This reduces the pull of emotional or stress-driven snacking, making it easier to stick to healthier food choices. With cravings diminished, you can maintain consistency and progress toward long-term goals.
Tesofensine boosts norepinephrine levels, which activate the sympathetic nervous system and modestly increase basal metabolic rate. This means your body burns slightly more calories at rest, complementing the reduction in calories from appetite control. The combined effect creates a stronger calorie deficit, which is key for fat loss.
Beyond appetite and metabolism, Tesofensine’s action on neurotransmitters can support sharper focus and more consistent daily energy. This helps reduce the fatigue or mental fog often associated with dieting, keeping you motivated and productive. With better energy balance, it’s easier to commit to activity, meal prep, and lifestyle changes that maximize results.
What Is Berberine?
Berberine is a plant-derived compound with powerful metabolic effects. It activates AMP-activated protein kinase (AMPK)—boosting muscle glucose uptake, increasing fatty-acid oxidation, and inhibiting fat storage. It also improves insulin sensitivity, can modulate the gut microbiome, and reduces hepatic glucose production—all of which stabilize blood sugar and support fat loss.
Brain & Behavior
Tesofensine helps reduce calorie intake by improving satiety and dialing down cravings.
Metabolic Optimization
Berberine improves blood sugar control and energy utilization, helping your body burn calories more efficiently and store less fat.
Together they target central appetite control + metabolic performance for a dual-pathway fat-loss strategy and more stable energy/mood.
Please reach us at info@salishshorewellness.com if you cannot find an answer to your question.
Tesofenisine is generally well-tolerated, though it can have stimulant-like effects in some individuals. You may notice temporary changes such as slight restlessness or changes in sleep during the first few days. If you ever feel unsure, our clinic is here to support you and adjust your plan as needed.
Many clients notice reduced cravings and improved portion control within the first 1–2 weeks. Weight loss results typically become more noticeable after consistent use paired with hydration, protein-forward meals, and light daily activity. Staying consistent with your routine is the key to sustainable results.
Yes—Tesofensine works best when paired with lifestyle support. We recommend at least 64 oz of water per day, prioritizing protein in your meals, and incorporating light to moderate daily movement. These simple steps help maximize both fat loss and energy balance.
Tesofensine primarily targets appetite and satiety by influencing brain neurotransmitters, helping you reduce calorie intake. Berberine complements this by improving insulin sensitivity, stabilizing blood sugar, and boosting fat metabolism. Together, they create a dual-action approach: appetite control plus enhanced metabolic support for more efficient weight loss.
Some people may experience mild, temporary effects like restlessness, sleep changes, or digestive adjustments as the body adapts. These usually improve over time and can often be minimized by taking your dose in the morning. Our team will walk you through what to expect and support you throughout your treatment.
Tesofensine is often paired with Berberine for enhanced results, but combining it with other prescription medications depends on your health profile. During your consultation, we’ll review your medical history and make sure your plan is safe and effective. Always check with your prescribing provider before mixing treatments.
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